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HUMAN-cow embryos have been created in a world
first at Newcastle University in England, hailed by the scientific
community, but labelled "monstrous" by opponents.
A team has grown hybrid embryos after injecting human DNA into eggs
taken from cows' ovaries, which had most of their genetic material
removed.
The embryos survived for three days and are intended to provide a
limitless supply of stem cells to develop therapies for diseases such
as Alzheimer's, Parkinson's and spinal cord injuries, overcoming a
worldwide shortfall in human embryos.
Dr Teija Peura, director of human embryonic stem cell laboratories
at the Australian Stem Cell Centre, said somatic cell nuclear transfer
(SCNT) had been done between animal species, but the "99 per cent
human" embryos could boost research.
"If successful, they
would provide an important additional research tool to help realisation
of stem cell-based therapies for human diseases," Dr Peura said.
"All
avenues of research, including SCNT . . . need to be encouraged if we
want to fulfil the promises of stem cell technologies."
But
her colleague, Dr Andrew Laslett, warned the process was yet to yield a
stem cell line and so it remained only an academic possibility.
In
January, the Fertilisation and Embryology Authority gave Newcastle
University a licence to do the work, but the British Parliament would
debate the longer-term future of such research next month.
Under the licence, embryos are not allowed to be developed beyond 14 days.
Preliminary
findings of the embryo program were presented in Israel last week, and
the head of the university's Institute of Human Genetics, Prof John
Burn, said further evaluation would be done before the full details
were published.
"If the team can produce cells which will
survive in culture, it will open the door to a better understanding of
disease processes without having to use precious human eggs," Prof Burn
said.
"Cells grown using animal eggs cannot be used to treat
patients on safety grounds, but they will help bring nearer the day
when new stem cell therapies are available."
The Catholic
Church in Britain branded the creations as "monstrous" - a view
supported by Caroline Chisholm Centre for Health Ethics director Fr
Kevin McGovern.
"An almost-human embryo is being created and then it's being destroyed," he said.
"I cannot see that that respects human life or the dignity of human life.
"Human beings - or even almost human embryos - are not just things that you can use in a laboratory experiment.
"What is being created is life.
"No one knows exactly what would grow from these embryos.
"If
this is approved in the UK, there will be renewed pressure to permit it
here, and we will travel further down the slippery slope of allowing
just about anything."
It is not the first time hybrids have been created.
The
method was pioneered by Dr Hui Zhen Sheng's team at the Shanghai Second
Medical University, China, where she fused human cells with rabbit eggs
to produce early stage embryos, which in turn yielded human stem cells.
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